WAVE® System 4500-R

The WAVE® System Model 4500HT is designed with higher through-put labs in mind and has the ability to analyze samples twice as fast as the standard WAVE® 4500 System. The WAVE® System is one of the most sensitive and accurate technologies for sequence variant analysis and separation of nucleic acid fragments. The WAVE® 4500HT System is fully automated, from sample collection to results analysis. Navigator™ Software creates the fragment specific methods, controls the instrument and analyzes your results. Fragment separation is achieved by the patented DNASep® HT Cartridge technology.

SKU: NAV-99-4500-AR/BR Category:

Product Description

The WAVE® System Model 4500HT is designed with higher through-put labs in mind and has the ability to analyze samples twice as fast as the standard WAVE® 4500 System. The WAVE® System is one of the most sensitive and accurate technologies for sequence variant analysis and separation of nucleic acid fragments. The WAVE® 4500HT System is fully automated, from sample collection to results analysis. Navigator™ Software creates the fragment specific methods, controls the instrument and analyzes your results. Fragment separation is achieved by the patented DNASep® HT Cartridge technology.

The fragments pass through the system’s ultraviolet detector and absorbance is recorded over time. This information is processed by the Navigator Software suite. It records the results in the form of chromatograms that can be further analyzed and filed by Navigator.

The WAVE® System 4500 series of  DHPLC instruments are one of the most sensitive and accurate technologies for sequence variant analysis and separation of nucleic acid fragments. As a proven technology, the WAVE® System is used by many of the world’s leading medical centers. The WAVE® System 4500 models are fully automated, from sample collection to results analysis. Navigator™ Software creates the fragment specific methods, controls the instrument and analyzes your results. Fragment separation is achieved by the patented DNASep® Cartridge or DNASep® HT Cartridge technology.

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WAVE® 4500 System Models

The following are the three WAVE® System 4500 models available:

  • WAVE® System Model 4500: designed for laboratories with low through-put that want the benefits of DHPLC technology.
  • WAVE® System Model 4500HT: designed with higher through-put labs in mind and has the ability to analyze samples twice as fast as the standard WAVE® 4500 System. 
  • WAVE® System Model 4500HT-HS: designed with higher through-put labs that also require the most sensitive analysis possible for low-level mutation detection. The WAVE® 4500HT-HS System has the ability to analyze samples twice as fast as the standard WAVE® 4500 System. This system includes the WAVE® HSD – High Sensitivity Detector.

WAVE® System Support Plans

ADS BIOTEC provides a wide range of WAVE® Customer Support Plans to allow you to experience the maximum benefit from your ADS BIOTEC WAVE® System. WAVE® Customer Support Plans provide different levels of maintenance, support and training allowing you to select what is required for your laboratory. Whether you are a low, medium or high throughput laboratory, we have a support plan to meet your needs.

WAVE® System Warranty

ADS BIOTEC WAVE® Systems are warranted to be free from defects in material and workmanship for twelve months following installation, or fourteen months following shipment, whichever occurs first.

Coverage Summary

Preventative maintenance visit.
Emergency visits to address operational failures including parts, labor, and travel expenses at no charge.
Telephone Hotline Support.
Software revisions.
ADS BIOTEC does not replace parts under a no-charge order if there is fault or negligence by the customer through missuse or accident.
The following items are not covered: operator error, chemistry or application issues, spare parts, post installation training, optional accessories or their installation, and IQ/OQ/PQ services.

Warranty Terms

Products are supplied for research use only. ADS BIOTEC warrants the Products are free from defects in material and manufacture and conform to ADS BIOTEC’s specifications at the time of shipment. Subject to verification by ADS BIOTEC, if any Product fails to conform to the specifications or any defect in material or manufacture appears: 1) for Products which are scientific instruments within one (1) year from the date of installation; and 2) for related Consumable Products, modules and parts within 30 days from the date of shipment, ADS BIOTEC’s entire liability and Customer’s exclusive remedy shall be, at ADS BIOTEC’s sole discretion, the repair or replacement of the defective Products.

Limitations to Warranty

Unless a separate service plan is purchased, all regularly scheduled maintenance and repairs during the Warranty term shall be the responsibility of Customer. This warranty does not cover any damage to Products due to misuse, improper site selection, and maintenance or operation by Customer or any others which is contrary to recommended instructions and design parameters for the Products. This warranty does not cover damage or defects resulting from repair or relocation of the Products by anyone other than a ADS BIOTEC representative. After the initial installation of the Products any post installation realignment, readjustment, recleaning, or recalibration, unless due to defects in material or workmanship, are the responsibility of Customer. Certain items which are refurbished or otherwise reconditioned are also excluded from the terms of this warranty. This warranty does not cover any damage due to accidents, vandalism, fire, flood, other environmental factors or any other Force Majeure. If you have questions regarding warranty coverage, please contact ADS BIOTEC Customer Service.

The warranty further excludes items supplied by third party manufacturers, such as computers and related software. Customer is responsible for any modifications to the computers or software including, but not limited to: interfacing or networking; unauthorized hardware modifications; repartitioning or reformatting of the hard drive; installation or modification of additional or new hardware; and installation or reinstallation of new or existing computer operating systems or service packs.

THIS WARRANTY IS MADE IN LIEU OF ALL OTHER WARRANTIES, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE; ANY IMPLIED WARRANTY ARISING OUT OF A COURSE OF DEALING OR OF PERFORMANCE, CUSTOM OR USAGE OF TRADE; OR ANY IMPLIED WARRANTY AGAINST PATENT INFRINGEMENT. UNDER NO CIRCUMSTANCES SHALL TRANSGENOMIC BE LIABLE FOR DAMAGES OF ANY KIND, INCLUDING WITHOUT LIMITATION, DIRECT, INDIRECT, INCIDENTAL, SPECIAL OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, LOSS OF PROFITS, REVENUE OR BUSINESS) RESULTING FROM OR IN ANY WAY RELATED TO THE PRODUCTS. These limitations apply regardless of whether such damages are sought based on breach of contract, negligence, strict liability in tort, or any other legal theory. The liability of ADS BIOTEC relating to any order by Customer shall in no event exceed the total amount of the payments received by ADS BIOTEC relating to such order. Without regard to any applicable statute of limitations, Customer agrees that any legal action related to any order must be commenced within ninety (90) days of the purchase date.

By placing their order, Customers represent and warrant that they and their employees and agents shall comply with all applicable laws, ordinances, regulations and codes in handling, storage and use of Products and shall indemnify and hold harmless ADS BIOTEC from any claims, rights or causes of action related thereto, or to Customer’s failure act in accord with these terms and warranties.

To the best of its information and belief, ADS BIOTEC has the necessary intellectual property rights to make the Products. Please contact the ADS BIOTEC Law Department at 7409 Irvington Road, Omaha, NE 68122 with any specific questions. While information and data presented are accurate and reliable to the best of ADS BIOTEC’s information and belief, ADS BIOTEC does not guarantee the accuracy of any information and data, nor do we represent that reliance upon such information and data will ensure compliance with any applicable laws and regulations.

ADS BIOTEC reserves the right to alter these terms and conditions at any time and without notice to Customer. Any variance of these terms is not valid unless it is in writing and signed by an officer or other authorized representative of ADS BIOTEC. If you have questions regarding your warranty coverage, please contact ADS BIOTEC Customer Service.

SoftwareNavigator™ Software
  • Internet connectivity for retrieval of genetic sequences
  • Automated prediction of melt temperatures
  • Complete system operating parameters
  • Data analysis and automated mutation calling
  • Network capabilities
Separation  CartridgeDNASep® HT Cartridge

Patented column filled with non-porous matrix consisting of polystyrene-divinylbenzene (PS-DVB) copolymer microspheres

  • Injection capacity: 0.5 ng to 4 µg
Computer SystemCPU
  • Intel® Pentium® 4 Processor 2.80 GHz
  • Microsoft® Windows® XP Professional
  • Microsoft® Office 2003 Basic
  • Small Form Factor Desktop CPU
  • 1 GB PC2-4200 (DDR2-533) 2 x 512
  • 160 GB Serial ATA 7200 RPM
  • 1.44 MB floppy drive SFF
  • 16X DVD+/-RW drive (LS/DL/DF)
  • Integrated Broadcom Gigabit NIC
  • PS/2 keyboard
  • PS/2 scroll mouse
  • Country Kit dc 7600
  • 2nd Serial Port Adapter LP
  • Dc7600 Restore CD
  • HP ProtectTools password security software
  • Three years parts and labor
  • Three years next business day onsite-Limited Warranty
  • Monitor

17" flat panel display with integrated speakers

Printer

HP DeskJet 5650 Color Inkjet Printer with Universal Power Supply

PumpLow Pressure Gradient Solvent Delivery System
  • Delivers up to four separate buffers
  • Flow rate control: 0.1 - 1.5 ml/min
  • Flow rate accuracy: ± 2% (H2O at 20 °C)
AutosamplerTriple plate capability:
  • 2 x 96 samples
  • 3 x 96 samples (optional)
  • 3 x 384 samples (optional)
  • Integrated Accelerator

Temperature control: Factory present 14 °C ± 1 °C
Adjustable: 4 °C to ambient
Sample volume: 200 µL max. on 96-well plate, higher on optional 48 well-plate
Injection volume: 1 - 450 µL; up to 2 mL with optional syringe

Oven
  • Temperature range: ambient to 40 °C to 100 ºC
  • Temperature precision: 0.1 ºC  increments over entire temperature range
  • Reproducibility: ± 0.1 °C
  • Linearity over full temperature range: ± 0.1 °C
  • Heat and cool rate: Better than 1°C/min
  • High Precision Peltier
DetectorUV/Vis
  • Wavelength range: 200-600 nm
  • UV Source: Deuterium lamp
Dimensions34 cm W x 50 cm D x 101cm H
(14" W x 20" D x 40" H)
Weight: 80 kg (180 lb)

The FCW 210 WAVE® Fragment Collector may be added to the WAVE® System Model 4500 HT-HS to extend its capabilities.
 

FCW 210 WAVE® Fragment Collector
FCW210

The ADS BIOTEC WAVE® Fragment Collector Model FCW 210 enables fully automated purification of nucleic acids with the WAVE® System. Nucleic acid samples collected by the FCW 210 meet high purity and sample concentration requirements for use in molecular genetic analyses and genomics. The dual plate FCW 210 enables fully automated fractionation and purification of ss- and dsDNA, RNA, and synthetic oligonucleotides with minimum sample loss and minimum cross contamination.

The FCW 210 is controlled by Navigator™ Software which enables collection of nucleic acid fragments including:

  • Minimum detection threshold above baseline with proprietary baseline drift compensation
  • Time/eluant volume window around peak retention time
  • User-defined collection time windows

Design refinements in the FCW 210 include a proprietary flow drop control system that delivers:

  • Minimum sample loss
  • Minimum cross contamination
  • Precise drop volume control
  • Maximum sample concentration

The WAVE® System with the optional Fragment Collector FCW 210 is a robust reliable system for the fractionation and purification of ss- and ds-DNA, RNA and synthetic oligonucleotides.

An additional feature of the FCW 210 is the ability to chill plates (10 + 2 ºC).

 

Complete High Throughput System includes: (1) HPLC Pump with internal degasser and low-pressure gradient system, (1) Triple Plate (capable) AutoSampler, (2) 96-well Sample Trays, (1) High precision L-2310T Cartridge Oven, (1) High Sensitivity UV Detector, (1) Rapid Analysis package, (1) Computer Work Station w/ Navigator Software, and (1) DNASep HT Cartridge.

WAVE Premier Support Plan
WAVE Basic Service Plan
WAVE Non-contracted Services
WAVE Applications and Training Plan
WAVE Preventative Maintenance Visit
WAVE System Warranty
Using the WAVE HS System in Clinical Microbiology–RISA Analysis of Infectious Pseudomonas Species
WAVE 4500 System
WAVE HT System Premier Support Plan

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